Harvard researchers say COVID-19 vaccines could permanently alter human genomic DNA

at 30.12.2021
A team of researchers from Harvard University and the Massachusetts Institute of Technology (MIT) published a study in December 2020 demonstrating that SARS-CoV-2 virus RNA can be reverse transcribed in human cells and that these sequences can be integrated into the human genome. The discovery is critical in resolving the scientific difficulty of whether messenger RNA in new COVID vaccines can enter the cell nucleus and alter DNA.

Under normal circumstances, how does messenger RNA function? First, it "transcribes" a DNA strand's genetic information, then travels outside the nucleus to the cytoplasm, where it "translates" the instructions about the proteins it must produce, and then decomposes. Unlike natural messenger RNA, the new vaccines' synthetic messenger RNA is delivered directly to the cytoplasm, where it "translates" the instructions to produce Spike protein.

According to the Centers for Disease Control and Prevention (CDC) and many new vaccine specialists, messenger RNA's role would end here in the "translation" phase, decomposed immediately after transmission, before it had time to penetrate the nucleus. Vaccines based on messenger RNA "do not affect or interact in any way with DNA," according to CDC officials, because the mRNA "cannot penetrate the cell nucleus where the DNA is." Is that correct?

In December 2020, a group of scientists from Harvard University and the Massachusetts Institute of Technology (MIT) published the results of their research into the possibility that the new Coronavirus RNA could be reverse transcribed by the body in a preprint study [2]. According to the researchers, their approach was justified because "they were surprised to see that a significant number of those who were cured of COVID-19 had positive results on PCR tests long after healing." The most important discovery is that SARS-CoV-2 RNA "can be reverse transcribed in human cells" and that "these DNA sequences integrate into the cell's genome" (a phenomenon called retro-integration).

Dr. Doug Corrigan, a specialist in Biochemistry and Molecular Biology, notes in a review [3] of the study that this finding is critical for the functioning of messenger RNA-based vaccines, which, like the wild-type virus, could permanently alter genomic DNA through reverse transcription. The phenomenon suggests that DNA can instruct RNA (transcription) and reverse transcription. Enzyme enzymes called reverse transcriptases convert RNA into DNA (reverse transcription), causing RNA to be integrated into DNA.

According to Harvard-MIT researchers, endogenous reverse transcriptase enzymes facilitate the reverse transcription of Coronavirus RNAs and trigger their integration into the human genome. A 2012 study [4] shows that the integration of the viral genome could have dramatic consequences for the host cell, including gene alteration, insertional mutagenesis, and cell death. The Harvard-MIT study [5] warns that the effects of this phenomenon can be severe, resulting in "a more severe immune response, such as cytokine storms or autoimmune reactions," demonstrating the need for further clinical research.

The study's findings, according to Doug Corrigan, raise serious concerns. The amount of burning is proportional to how long the synthetic messenger RNA remains in the body and causes Spike protein production. There is no scientific evidence that "Spike protein will only be expressed for a short period (1-3 days) after vaccination because it is unknown how long the synthetic messenger RNA of vaccines will remain in the body," he claims. Furthermore, synthetic messenger RNA does not function similarly to natural messenger RNA. After decades of research, scientists have learned how to modify messenger RNA to increase its stability and longevity chemically. As a result, synthetic RNA "remains in the cell for a longer period than viral RNA or RNA that our cells normally produce for normal protein production." Furthermore, synthetic RNA, which is designed to be more efficient in the "translation" process, can increase the frequency and severity of the negative effects when compared to the natural virus. 

Many unanswered questions remain. What processes, for example, will the vaccine activate in people who have had COVID and have already had their genome altered by wild-type RNA? Will the vaccine not elicit a severe immune response in response to the virus's "passing through"? How will the vaccinated body react when it encounters the wild-type virus? These questions are still waiting for an answer, and hopefully, future research will clarify them.  



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